K. Ralovich, L. Itu, V. Mihalef, P. Sharma, Razvan Ioan Ionasec, D. Vitanovski, W. Krawtschuk, A. Everett, R. Ringel, N. Navab, D. Comaniciu Hemodynamic Assessment of Pre- and Post-Operative Aortic Coarctation from MR Images Proceedings of the 15th International Conference on Medical Image Computing and Computer Assisted Interventions (MICCAI), Nice, France, October 2012 (bib)
	Coarctation of the aorta (CoA?), is a congenital defect characterized by a severe narrowing of the aorta, usually distal to the aortic arch. The treatment options include surgical repair, stent implantation, and balloon angioplasty. In order to evaluate the physiological significance of the pre-operative coarctation and to assess the post-operative results, the hemodynamic assessment is usually performed by measuring the pressure gradient (dP) across the coarctation site via invasive cardiac catheterization. The measure of success is reduction of the (dP < 20 mmHg) systolic blood pressure gradient. In this paper, we propose a non-invasive method based on Computational Fluid Dynamics (CFD) and MR imaging to assess the pre- and post-operative hemodynamics for both native and recurrent coarctation patients. High correlation of our results and catheter measurements is shown on corresponding pre- and post-operative examination of 5 coarctation of the aorta patients.
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