MoritzBlume

Chair for Computer Aided Medical Procedures & Augmented Reality
Lehrstuhl für Informatikanwendungen in der Medizin & Augmented Reality

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Moritz Blume

Technische Universität München
Boltzmannstr. 3
85748 Garching bei München
Germany

OR

Institute of Particle Physics - IFIC
Edificio Institutos de Investigacion
Apartado de Correos 22085
E-46071 Valencia
Spain


fon: +34 9635 43237
room no.: 111


Research Topics

My general research interests are image restoration and reconstruction in medical imaging. Especially, I am interested in multi-view deconvolution and image reconstruction for positron-emission-tomography (PET).

Multi-View Deconvolution

"Wer misst misst Mist" - direct translation into english (trying to conserve the alliteration...): "Whoever measures measures muck". Free translation into english: "measurements are error-prone". Whoever tried to measure a physical quantity knows about the truth of this phrase. Measuring devices that everyone of us knows are digital cameras, microscopes, ultrasound... however, even if the images taken by a digital camera look quite good, the introductory phrase holds: measurements are error-prone.

I am looking at blurring. In many biomedical applications, blurring depends on the point of view. For example, two observations from two different points of views of a 3D microscope could look like this:

Each observation offers additional information about the original image. Already on the base of these two observations, my algorithm yields the following restored image:

This restoration is done without any knowledge about the degradation process. Such methods are also called blind deconvolution methods. Even more realistic scenarios - like shift-variant blurring - can be tackled with our method. For more details, please refer to the literature listed below.

Positron-Emission-Tomography Motion Compensation

Positron-emission-tomography (PET) is nowadays a well-established tool for diagnosing, staging and monitoring diseases in patients. However, due to the long acquisition times which are necessary for a PET scan, patient movements are often unavoidable. Patient motion during data acquisition can cause image blurring and severe artifacts in the reconstructed image, thus posing a significant problem for further diagnosis and treatment.

Reconstruction algorithms that incorporate patient motion are still at a premature level. My interest is to improve known methods, e. g. by incorporating partial motion information.


Open Diploma Thesis

Multi-modal image registration for PET/MRT

Image registration - the task where two images are aligned to each other - is a commonly used method in many biomedical applications. The goal is often to be able to better compare images acquired at different points in time. Even more interesting is the case where the two images arise from different modalities, for example one from positron-emission-tomography (PET) and one from magnet-resonance-tomography (MRT). After registration, anatomical information from the MR images can be augmented by functional information of the PET images.

The goal of this thesis is to develop a (semi) automatic method that registers three dimensional PET and MR images for rat brains in order to validate mathematical models for tracer binding. Currently registration is done manually and takes approximately three hours. Since the problem is not solved for this application, a publication in an international conference/journal is aimed at.

Anyone interested in this work please contact me via email or phone and we arrange a short meeting in order to discuss more details!


Publications

2009
M. Blume, A. Keil, N. Navab, M. Rafecas
Blind Motion Compensation for Positron-Emission-Tomography
SPIE Medical Imaging, Orlando, Florida, USA, Feburary 2009 (bib)
M. Blume, A. Martínez-Möller, A. Keil, N. Navab, M. Rafecas
Joint Reconstruction of Image and Motion in Gated Positron-Emission-Tomography
10th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine, Beijing, China, September 2009 (bib)
T. Felder, M. Blume, J. Oliver, M. Rafecas
ML-EM Implementation on a GPU: Avoiding Simultaneous Read-Modify-Write Processes
10th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine, Beijing, China, September 2009 (bib)
2008
M. Blume, M. Rafecas, S. Ziegler, N. Navab
Combined Motion Compensation and Reconstruction for PET
Proc. IEEE Nuclear Science Symposium and Medical Imaging Conference, Dresden, Germany, October 2008 (bib)
2007
W. Wein, M. Blume, U. Leischner, H.-U. Dodt, N. Navab
Quality-based Registration and Reconstruction of Optical Tomography Volumes
Medical Image Computing and Computer-Assisted Intervention (MICCAI 2007), Brisbane, Australia, October 2007 (bib)
M. Blume, D. Zikic, W. Wein, N. Navab
A New and General Method for Blind Shift-Variant Deconvolution of Biomedical Images
Medical Image Computing and Computer-Assisted Intervention (MICCAI 2007), Brisbane, Australia, October 2007 (bib)


Masters Thesis (Diplomarbeit)

M. Blume, D. Zikic, W. Wein, N. Navab
Multi-View Deconvolution of Biomedical Images
Technische Universität München, 2007


Reports and Tutorials

M. Blume, W. Wein, U. Leischner, H. U. Dodt, N. Navab
Image Registration and Merging for a new Optical Tomography
Technische Universität München, 2005.
M. Blume
Expectation Maximazation: A Gentle Introduction
Technische Universität München, 2008.
M. Blume
Expectation Maximization for Emission Tomography
Technische Universität München, 2008.
M. Blume
An Introduction to Probability Theory
Technische Universität München, 2008.


Private Stuff - My Favorite Links

atmosfair Frequent flyer? This non-profit organization tries to reduce the environmental damage of flying by building solar kitchens for rice cooking in africa which are supposed to replace the currently used diesel aggregates. Enter your flight details and the page tells you how much exactly you have to donate in order to compensate your flight. I talked to some people and they said that this is just a new form of selling of indulgences. However, it is the second best solution to the problem after the best solution: simply not to fly.
fasterplan For organizing spare time events! It allows a group of friends to find a common date and to vote for what to do. Also links and pictures can be placed. I really recommend it to anyone who is sick of writing thousands of emails just in order to bring five people to the same place at the same time!
deezer I couldn't believe it when I first heard of it: listen to any music for free and legally. Of course, the quality is not that good...
the daily moe Private blog about a german's life in Spain... wink


UsersForm
Title: Dipl.-Inf. Univ.
Firstname: Moritz
Middlename:  
Lastname: Blume
Picture: blumemoritzicon.png
Birthday:  
Nationality: Germany
Languages: English, German, French, Spanish
Groups: Medical Imaging, Molecular Imaging
Expertise:  
Position: Scientific Staff
Status: Active
Emailbefore: blume
Emailafter: cs.tum.edu
Room: MI 03.13.058
Telephone: +49 89 289 19403
Alumniactivity:  
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Personalvideotext01:  
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Edit | Attach | Refresh | Diffs | More | Revision r1.37 - 07 Nov 2008 - 16:58 - MoritzBlume

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